Thymosin Alpha-1 10mg — Immune Modulation & Longevity Research Peptide
Thymosin Alpha-1 (Tα1, also known as Thymalfasin) is a 28-amino acid naturally occurring peptide originally isolated from thymic tissue. First characterized by Dr. Allan Goldstein at the National Cancer Institute, Thymosin Alpha-1 has developed one of the most compelling clinical evidence bases of any research peptide — including approval in 37+ countries as Zadaxin for hepatitis B and C, cancer immunotherapy support, and severe infections.
H&J Pharma supplies Thymosin Alpha-1 at 10mg per vial with HPLC-verified ≥99% purity for qualified research applications.
Product Overview
Thymosin Alpha-1 is an endogenous immunomodulatory peptide that promotes T-cell maturation and differentiation, enhances dendritic cell function, activates natural killer (NK) cells, and upregulates toll-like receptor (TLR) signaling. Its primary mechanism is the enhancement of both innate and adaptive immune responses — positioning it as one of the most versatile immune-modulating peptides in research. It also demonstrates anti-inflammatory properties and has been studied for its role in autophagy induction, particularly relevant to longevity science.
Key Benefits
- T-cell enhancement — promotes T-lymphocyte maturation, differentiation, and proliferation
- NK cell activation — enhances natural killer cell cytotoxicity against infected/malignant cells
- Dendritic cell function — improves antigen presentation for adaptive immune responses
- TLR pathway activation — upregulates innate immune signaling via TLR-2, TLR-4, TLR-9
- Antiviral research — approved for hepatitis; studied for broad antiviral immune enhancement
- Cancer immunotherapy — studied as an adjunct to chemotherapy and immunotherapy protocols
- Autophagy induction — studied for its role in cellular cleanup relevant to longevity
- Immune aging (immunosenescence) — restores immune function in aged subjects in research
Popular Use Cases
Thymosin Alpha-1 research spans infectious disease immunology, oncology, aging immunology (immunosenescence), autoimmune research, and longevity science. Its clinical approval history — in hepatitis B, hepatitis C, and critical illness contexts — provides an exceptionally strong evidence base for its immune-modulating mechanisms.
Who Commonly Uses This
Immunologists, infectious disease researchers, oncologists, gerontologists studying immunosenescence, and longevity researchers represent the primary scientific communities for Thymosin Alpha-1. Its clinical history also attracts clinicians interested in translational immune research.
Product Details
| Peptide | Thymosin Alpha-1 (28 amino acids) |
| Content | 10mg per vial |
| Format | Lyophilized powder |
| BAC Water | Included |
| Purity | ≥99% HPLC verified |
| Storage | 2–8°C, away from light |
| Research Use | For laboratory and research purposes only |
Storage & Handling
Store at 2–8°C away from light. Avoid freeze-thaw cycles. Once reconstituted, refrigerate and use within 28–30 days.
Research & Scientific Interest
Thymosin Alpha-1 has accumulated an extraordinary clinical and preclinical evidence base. Approved in 37+ countries as Zadaxin, it has demonstrated efficacy in hepatitis B/C, been studied in HIV, cancer immunotherapy, sepsis, COVID-19, and influenza. Preclinical research shows it restores immune function in aged subjects, induces autophagy, and enhances cytokine profiles relevant to longevity — making it one of the most clinically grounded immune-modulating peptides available for research.
Frequently Asked Questions
Thymosin Alpha-1 is a 28-amino acid thymic peptide that modulates both innate and adaptive immunity. Approved in 37+ countries (as Zadaxin), it is researched for T-cell enhancement, NK cell activation, antiviral activity, cancer immunotherapy, and immune aging.
Zadaxin is the brand name for Thymalfasin — the pharmaceutical form of Thymosin Alpha-1. It is approved in 37+ countries for hepatitis B, hepatitis C, and as an immunotherapy adjunct in cancer treatment, giving Thymosin Alpha-1 one of the strongest clinical evidence bases of any research peptide.
It promotes T-cell maturation and differentiation, activates NK cells, enhances dendritic cell antigen presentation, and upregulates TLR-2, TLR-4, and TLR-9 signaling — providing comprehensive enhancement of both innate and adaptive immune responses.
Yes. Thymosin Alpha-1 is studied for immunosenescence (age-related immune decline) reversal, autophagy induction, and maintenance of immune surveillance — all relevant to the biology of healthy aging and longevity.
Yes. Each vial includes bacteriostatic water for reconstitution.
Store at 2–8°C away from light. Once reconstituted, refrigerate and use within 28–30 days.
No. Strictly for laboratory and research purposes only.
Yes. H&J Pharma offers same-day shipping with next-day delivery across Vietnam.
Research References
- Goldstein AL, et al. “Thymosin alpha 1: biological activity and clinical applications.” Science. 1977. PubMed
- Thymalfasin Study Group. “Randomized double-blind trial of thymalfasin in hepatitis B.” Hepatology. 1997.
- Garaci E, et al. “Thymosin alpha 1 induces the antiviral TH1 immune response.” J Immunol. 2000.
- Shrivastava R, et al. “Thymosin Alpha-1: mechanisms and clinical indications.” Expert Opinion on Biological Therapy. 2016.
- Pica F, et al. “Serum thymosin alpha 1 levels in COVID-19 patients.” Clinical Immunology. 2021. PubMed
- Dominari A, et al. “Thymosin alpha 1 as a COVID-19 adjunct therapy.” World Journal of Virology. 2021.
- Goldstein AL, Goldstein AL. “From laboratory to clinic: the development of thymosin alpha 1.” Expert Opinion on Biological Therapy. 2009. PubMed
- Romani L, et al. “Thymosin alpha 1 activates autophagy as an innate immune mechanism.” Immunity. 2012. PubMed
- Rasi G, et al. “Combined thymosin alpha 1 and interferon for hepatitis C.” Clinical Therapeutics. 1996.
- Moody TW, et al. “Thymosin alpha 1 effects on human natural killer cells.” J Clin Oncol. 1994.
Lifestyle & Wellness Context
Thymosin Alpha-1 stands among the elite tier of clinically validated research peptides. With approval in 37+ countries, a 40+ year research history, and emerging applications in longevity and COVID-19, Tα1 represents the convergence of immune science and precision wellness. H&J Pharma supplies it at research grade with same-day shipping across Vietnam.
Related Wellness Research Areas
Communities studying immunology, antiviral biology, cancer immunotherapy, immunosenescence, autophagy, longevity medicine, and infectious disease will find Thymosin Alpha-1 one of the most clinically grounded immune peptides in research.
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